Jitotene 20 Tablet (10 Tab)

Medicine Information

Jitotene 20 Tablet Overview:

Jitotene 20 Tablet is an oral anti-diabetic medication primarily used to manage and control blood sugar levels in adults with Type 2 Diabetes Mellitus.

It contains Teneligliptin, belongs to the “Dipeptidyl Peptidase-4 (DPP-4) inhibitor “class of medications. It is typically prescribed when diet, exercise, and other lifestyle modifications are not enough to keep blood glucose levels within a healthy range.

In Type 2 Diabetes, the body either produces insufficient insulin or cannot effectively use it, often alongside the liver's overproduction of sugar. If left unmanaged, chronically high blood sugar can cause severe, long-term health complications, including heart disease, kidney damage, nerve pain, vision loss, and delayed wound healing.

Jitotene 20 works efficiently to lower blood glucose, particularly after meals, by boosting the natural incretin hormones (including GLP-1) that enhance insulin production and reduce excess sugar production by the liver. Additionally, it carries a low risk of weight gain or low blood sugar (hypoglycemia), making it a safe and efficient choice for daily diabetes management.

It is important to note that Jitotene 20 Tablet is not for treating Type 1 diabetes or diabetic ketoacidosis.

 

Composition:

Each film coated tablet contains- Teneligliptin Hydrobromide Hydrate eq. to Teneligliptin: 20 mg and Excipients q.s.

Colours: Quinoline Yellow WS & Titanium Dioxide.

 

Uses & Benefits of Jitotene 20 Tablet:

Jitotene 20 Tablet is used for the treatment of Type 2 diabetes mellitus or non-insulin-dependent diabetes mellitus (NIDDM), by improving glycemic control in adults whose blood sugar is not adequately managed by diet and exercise alone.

 

How Does Jitotene 20 Tablet Work:

The active ingredient of Jitotene 20 Tablet is Teneligliptin, a DPP-4 (dipeptidyl peptidase-4) inhibitor. It works by blocking the DPP-4 enzyme, which normally breaks down incretin hormones (such as GLP-1). By blocking these enzymes, Jitotene 20 increases the incretin levels and prolongs its action.

This action helps stimulate the pancreas to secrete more insulin when blood sugar levels are high and suppress the release of glucagon. This hormone causes the liver to produce excess sugar.

Together, these mechanisms dynamically lower blood glucose levels in a glucose-dependent manner.

 

Dosage of Jitotene 20 Tablet:

• Usage Direction

Take Jitotene 20 Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitotene 20 Tablet should be swallowed whole with water and not to be crushed, or chewed, preferably at the same time each day. Do not stop or alter the dose of Jitotene 20 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitotene 20, consult with your doctor or pharmacist.

• Missed Dose

In case you forget to take a dose of Jitotene 20 Tablet, take it as soon as you remember on that day. If it's nearly time for your next dose, simply skip the missed dose and proceed with your normal dosing schedule. Avoid taking two doses if you realize you've missed one. If you often frequently forget your medication, consult your doctor to reassess your dosing plan. Missing doses regularly can lead to undesired outcomes.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose

If you accidentally take more than the prescribed dose of Jitotene 20 Tablet, contact a physician or local poison control center immediately for standard supportive measures, including an ECG and symptomatic therapy. An overdose may cause severe hypoglycemia (very low blood sugar).

 

Contraindications of Jitotene 20 Tablet:

Do not take Jitotene Tablet if you have a known hypersensitivity or allergy to Teneligliptin or any of the components of this medicine. It must not be used by patients with Type 1 diabetes mellitus or diabetic ketoacidosis, including severe ketosis, diabetic coma or pre-coma.

Furthermore, it should be avoided during severe infections, major trauma, or undergoing surgery, as these critical situations typically require insulin therapy to safely and effectively manage blood sugar levels.

 

Precautions & Warnings of Jitotene 20 Tablet:

Before starting Jitotene 20 Tablet, consult your healthcare provider and discuss your complete medical history. Inform your physician if you have severe hepatic impairment, as it requires close medical monitoring.

Discontinue the medication and seek immediate medical attention if you experience persistent, severe abdominal pain (with or without vomiting), as this is a sign of acute pancreatitis.

While the risk of low blood sugar is low when Jitotene 20 is used alone, combining it with insulin or sulfonylureas increases the risk of hypoglycemia. Use with extreme caution if you have a history of heart failure, cardiac arrhythmias, bradycardia, or conditions prone to QT interval prolongation.

Additionally, special precautions are required for individuals with pituitary or adrenal insufficiency, malnutrition, starvation, irregular diets, or those performing strenuous physical exercise.

 

Side Effects of Jitotene 20 Tablet:

Jitotene 20 Tablet can cause side effects, though most are mild and temporary as your body adjusts. The most common symptoms are hypoglycemia and constipation. Other side effects may include headache, dizziness, diarrhoea, and pyrexia.

However, some rare serious side effects require immediate medical attention. These include gastrointestinal discomfort such as intestinal obstruction, abdominal pain, loss of appetite, increased amylase, and acute pancreatitis. Other rare or less frequent symptoms include elevated liver enzymes, proteinuria, uric acid, increased CK (CPK), increased serum potassium, eczema, wet rash, pruritus, and allergic dermatitis.

 

Safety Related Concerns of Jitotene 20 Tablet:

• Pregnancy

Jitotene 20 Tablet is not recommended during pregnancy unless explicitly prescribed by a doctor because its safe use in pregnant women has not been thoroughly established. This medicine should be used during pregnancy only if the anticipated benefit to the mother outweighs the potential risk to the fetus.

In many cases, healthcare providers may recommend switching to safer treatments, such as insulin, to maintain proper blood sugar control.

• Breastfeeding

Jitotene 20 Tablet should be avoided during breastfeeding, as it is unknown whether the ingredients could pass into the breast milk and affect the breastfed child.

Therefore, consulting with your doctor before taking Jitotene is crucial.

• Alcohol

Avoid or strictly limit excessive alcohol consumption while on this medication. Alcohol can significantly increase the risk of severe low blood sugar (hypoglycemia) and alter the effectiveness of diabetes management.

• Food Interactions

Jitotene 20 Tablet has no major food restrictions and can be taken with or without meals. However, maintaining a consistent, balanced diabetic diet is crucial for optimal results. To effectively regulate blood glucose levels and prevent sudden spikes, it is highly recommended to minimize high-glycemic-index foods, sugary items, refined carbohydrates, and also limit high-fat foods.

• Drug Interactions

Jitotene 20 Tablet can interact with various medications, which may alter their effectiveness or increase the risk of side effects. Inform your healthcare provider if you are taking other anti-diabetic medications, such as insulin or sulfonylureas, as combining those increases the risk of hypoglycemia and may require dose adjustments. Medications like salicylates, MAO inhibitors, and beta-blockers can enhance Jitotene's blood sugar-lowering effect. Conversely, steroids, adrenaline, and thyroid hormones can diminish its effectiveness, leading to elevated blood glucose. Furthermore, Class IA (e.g., quinidine sulfate hydrate, procainamide hydrochloride) and Class III (e.g., amiodarone hydrochloride, sotalol hydrochloride) antiarrhythmic drugs should be avoided or carefully evaluated due to the increased risk of QT interval prolongation.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving

Use caution while driving or operating heavy machinery, especially if you take Jitotene in combination with other anti-diabetic medications, as a sudden drop in blood sugar can cause dizziness, blurred vision, or impaired concentration.

 

Storage of Jitotene 20 Tablet:

Store at a temperature not exceeding 30°C. Keep out of reach of children.

Avoid using it after the expiry date, printed on the packaging. Dispose of expired or unused medication properly; do not throw it away casually.

 

 

Additional Information:

• Eat a balanced diet with whole grains, fiber, lean protein, and healthy fats. Limit sugary and processed foods.
• Exercise regularly for at least 150 minutes per week, such as brisk walking, swimming, or cycling.
• Monitor your blood sugar, HbA1c, cholesterol, and urine tests as advised by your doctor.
• Maintain a healthy body weight to help manage blood sugar levels.
• Carry a quick source of sugar to treat low blood sugar if needed.
• Do not stop or change your medication without consulting your doctor.
• Do not share your medicine with others, even if they have similar symptoms.
• Attend regular medical check-ups and follow your doctor's advice.

 

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Frequently Asked Questions (FAQs):

Q: Why is Jitotene 20 Tablet prescribed?

A: Jitotene 20 Tablet is prescribed to improve blood sugar control in adults with type 2 diabetes mellitus, helping to prevent the long-term complications associated with high blood glucose.

 

Q: Does Jitotene 20 Tablet cause weight gain?

A: No, Jitotene 20 (Teneligliptin) is considered weight-neutral. Unlike certain other anti-diabetic medications (such as sulfonylureas), it does not typically promote weight gain, making it an ideal choice for daily blood sugar management without impacting body weight.

 

Q: Is Jitotene 20 safe for individuals with kidney problems?

A: Yes, it is safe for patients with renal impairment or even end-stage renal disease, as no dose adjustments are required for patients with kidney complications.

 

Q: Can I stop taking Jitotene 20 once my blood sugar is under control?

A: No, you should not stop taking Jitotene 20 without consulting your doctor. Diabetes requires long-term management, and stopping the medication abruptly can cause your blood sugar levels to spike, increasing the risk of serious long-term diabetic complications.

 

Q: Can Jitotene 20 Tablet cause low blood sugar (hypoglycemia)?

A: When used alone, Jitotene 20 has a low risk of causing low blood sugar. However, if it is taken in combination with other anti-diabetic medications like insulin or sulfonylureas, the risk increases. Always look out for signs of low blood sugar, such as sweating, dizziness, and shaking.

 

Q: Can I consume alcohol while taking Jitotene 20 Tablet?

A: It is highly recommended to avoid or strictly limit alcohol consumption while taking this medication. Alcohol can alter blood glucose control and significantly increase the risk of severe low blood sugar (hypoglycemia) as well as adverse metabolic effects.

 

 

 

References:

1. ONLYGLIPTIN-20. Teneligliptin Tablets 20 mg. Accessed on: 14 July 2026. Click Here

2. TENELIGLIPTIN TABLETS 20mg (TILYPTIN 20). SUMMARY OF PRODUCT CHARACTERISTICS. Last Revised: April 2017. Accessed on: 14 July 2026. Click Here

3. AFOGLIP. Teneligliptin Tablets IP 20 mg. Torrentpharma. Last Revised: April 2021. Accessed on: 14 July 2026. Click Here

4. TENELISIGN (Teneligliptin Tablets 20 mg). SUMMARY OF PRODUCT CHARACTERISTICS. Accessed on: 14 July 2026. Click Here