Jitodieno 2 Tablet (10 Tab)

Medicine Information

Jitodieno 2 Tablet Overview:

Jitodieno 2 Tablet is a hormonal medication indicated for the management of pelvic pain associated with endometriosis.

Endometriosis is a painful gynecological condition characterized by the growth of tissue resembling the uterine lining outside of the womb.

Jitodieno Tablet is formulated with Dienogest, a synthetic progestin (artificial female hormone) that assists in managing abnormal tissue growth and reducing inflammation in the pelvic region.

Furthermore, it causes the endometrial tissue to shrink, effectively alleviating associated symptoms such as chronic pelvic pain and painful menstrual bleeding.

It may also be used for contraception when prescribed in combination with other specific medications.

 

Composition:

Each film coated tablet contains- Dienogest: 2 mg and Excipients q.s.

Colour: Titanium Dioxide

 

Uses & Benefits of Jitodieno 2 Tablet:

The therapeutic uses and benefits of Jitodieno 2 Tablet include:

• Treatment of Endometriosis: It is indicated to alleviate pelvic pain, painful periods (dysmenorrhea), and abdominal cramps caused by endometriosis. In this condition, tissue resembling the inner uterine lining grows outside the uterus.
• Prevention of Endometriosis Recurrence: It helps prevent the recurrence of endometriosis lesions and symptoms in patients who have undergone surgical intervention for the condition.
• Control of Heavy Menstrual Bleeding: It can help regulate and reduce heavy, irregular, or prolonged uterine bleeding associated with endometrial overgrowth.
• Birth Control: When used in combination with other specific hormonal medications, it can be utilized as an oral contraceptive to prevent pregnancy.

 

How Does Jitodieno 2 Tablet Work:

The active ingredient in Jitodieno Tablet is Dienogest, a synthetic form of the progestin (type of progesterone hormone). It functions by suppressing the effects of estrogen, which is the primary hormone responsible for the proliferation and growth of endometrial tissue.

By binding to specific progesterone receptors, Dienogest downregulates estrogen production. This action stops the uterine lining and displaced endometrial tissues from growing rapidly, ultimately reducing localized inflammation and pelvic pain.

 

Dosage of Jitodieno 2 Tablet:

• Usage Direction

Take Jitodieno 2 Tablet strictly as advised by your doctor, following the prescribed dose and timing. It can be taken at any time during your menstrual cycle. Jitodieno 2 Tablet should be swallowed whole with water without crushing, chewing, or breaking it, preferably at the same time each day. Do not stop or alter the dose of Jitodieno 2 Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitodieno 2, consult with your doctor or pharmacist.

• Missed Dose

If you forget to take a dose of Jitodieno Tablet, take it as soon as you remember that day. However, if it is close to your next scheduled dose, skip the missed one and continue your regular cycle. Do not attempt to take two doses if you have forgotten one. If you vomit or have diarrhea within 3 to 4 hours of taking it, treat it as a missed dose. Missing doses can frequently lead to undesired outcomes.

To prevent missing a dose, you might set reminders on your smartphone, use medication organizer boxes, or use other audio-visual technologies.

• Overdose

An accidental overdose rarely causes severe symptoms, but it can induce nausea, vomiting, or irregular vaginal bleeding. In case of an accidental overdose of Jitodieno 2 Tablet, immediately contact a physician or the poison control centre.

 

Contraindications of Jitodieno 2 Tablet:

Do not take Jitodieno 2 Tablet if you have a known allergy or hypersensitivity to Dienogest or any of the other ingredients in the medicine. It must not be used by individuals with active venous blood clots (thromboembolic disorders) or a history of severe arterial and cardiovascular diseases, including heart attack, stroke, or angina pectoris.

Additionally, it should be avoided in patients suffering from severe liver disease, active liver tumors (benign or malignant), or diabetes mellitus that has caused blood vessel damage. This medication is not advised for anyone with known, past, or suspected sex-hormone-dependent malignancies, such as breast or uterine cancer, nor should it be used to treat unexplained or undiagnosed abnormal vaginal bleeding.

Moreover, Jitodieno 2 Tablet is not indicated for pediatric patients before menarche (their first menstrual period) or for elderly patients over 65 years of age.

 

Precautions & Warnings of Jitodieno 2 Tablet:

Before starting treatment with Jitodieno 2 Tablet, it is essential to provide your healthcare provider with a comprehensive medical history. Because long-term use of Dienogest can decrease bone mineral density (BMD), specifically when prescribing this medication to adolescents between 12 and 18 years of age.

Extreme caution must also be exercised in patients with a history of depression or mood disorders, as exogenous hormonal fluctuations can potentially aggravate psychological symptoms.

Furthermore, individuals with a predisposition to chloasma (golden-brown skin pigmentation patches, particularly on the face) should strictly limit direct sunlight and ultraviolet (UV) exposure while undergoing therapy.

Additionally, while Jitodieno Tablet suppresses ovulation in many patients, it is not approved as a standalone contraceptive pill. Therefore, a reliable, non-hormonal barrier method (such as condoms) must be used concurrently if pregnancy is to be avoided.

 

Side Effects of Jitodieno 2 Tablet:

Certain side effects may occur with the Jitodieno 2 Tablet, but they are usually mild and temporary while your body adjusts to the medication. The most frequently reported symptoms include headaches, breast tenderness or swelling, acne breakouts, mild weight gain, and gastrointestinal disturbances such as nausea, abdominal pain, or bloating.

Hormonal fluctuations may also lead to changes in mood, including depressive symptoms, as well as irregular vaginal bleeding patterns, which can manifest as intermenstrual spotting, breakthrough bleeding, or altered menstrual cycles.

Although rare, serious adverse effects involving thromboembolic events require immediate emergency medical attention. Consult your healthcare provider right away if you experience signs of thrombosis (like unexplained cough, sudden breathlessness, severe chest pain, slurred speech, persistent dizziness, or fainting).

 

Safety Related Concerns of Jitodieno 2 Tablet:

• Pregnancy

Jitodieno 2 Tablet is contraindicated during pregnancy. While human data do not show a significant risk of birth defects if you take it accidentally in early pregnancy, it is still considered unsafe and is strictly avoided.

Additionally, if you become pregnant while taking this medication, there is a slightly higher chance that the embryo will develop outside the womb (an ectopic pregnancy). If you suspect you are pregnant, stop taking the tablet immediately and call your doctor.

• Breastfeeding

Jitodieno 2 Tablet is generally not recommended during breastfeeding, since Dienogest may passes into the breast milk and could potentially affect the breastfed child. Therefore, consulting with your doctor before taking Jitodieno 2 Tablet is crucial.

Alcohol

Data regarding the direct interaction between alcohol and Jitodieno 2 Tablet is limited. However, you should avoid excessive alcohol consumption while taking this medication. Both alcohol and Dienogest are metabolized by the liver, and concurrent heavy use can increase hepatic strain or alter the medication's clearance from your system.

• Food Interactions

Jitodieno 2 Tablet can be taken with or without meals as suggested. However, avoid consuming grapefruit juice while on this medication, as it can inhibit the enzyme that metabolizes Dienogest, leading to toxic levels of the drug in your bloodstream.

• Drug Interactions

Jitodieno 2 Tablet can interact with a wide range of medications, potentially altering its effectiveness or increasing the risk of toxicity. Its efficacy may decrease when taken concurrently with CYP3A4 enzyme inducers, such as rifampicin, phenytoin, carbamazepine, and St. John’s Wort—as they accelerate the breakdown of the drug.

Conversely, CYP3A4 inhibitors, including certain antifungals (e.g., itraconazole, voriconazole, and fluconazole), antibiotics (e.g., erythromycin and clarithromycin), and calcium channel blockers (e.g., diltiazem and verapamil), can raise Dienogest levels in the blood, increasing the risk of toxicity.

Additionally, other hormonal products, including contraceptive pills, or aromatase inhibitors should not be used concurrently unless explicitly told by your doctor. Always inform your healthcare provider about all current prescriptions, over-the-counter medications, and supplements to prevent potential interactions.

• Using Machinery & Driving

Jitodieno 2 Tablet is generally safe, as it does not typically affect your ability to drive or operate machinery. However, if you experience side effects such as dizziness, fatigue, or severe headaches, avoid driving or operating heavy equipment until you feel fully alert and steady.

 

Storage of Jitodieno 2 Tablet:

Store protected from light and moisture, at a temperature not exceeding 25°C. Keep out of reach of children.

Avoid using it once the expiry date on the packaging has been reached. Properly dispose of any expired or unused medications; do not discard them casually.

 

 

Additional Information:

• Incorporating foods rich in omega-3 fatty acids (like flaxseeds or fish), leafy greens, berries, and antioxidant-rich foods can help reduce global pelvic inflammation naturally.
• Minimizing caffeine, processed sugar, and trans-fats can alleviate hormonal fluctuations and severe cramping.
• Since Dienogest can affect bone mineral density, optimize its safety profile by engaging in light weight-bearing exercises and consuming adequate Calcium and Vitamin D supplements under medical supervision.
• Apply a heating pad or perform gentle pelvic yoga under medical supervision.
• Avoid stopping your medication suddenly unless instructed by your physician.
• Do not give your medicine to someone else who has the same symptoms, as it is a prescription medication.

 

 

Frequently Asked Questions (FAQs):

Q: Why Jitodieno 2 Tablet is prescribed?

A: Jitodieno 2 Tablet is a synthetic hormonal medication prescribed primarily to treat endometriosis. It works by regulating tissue growth and reducing localized inflammation, which helps effectively manage and alleviate painful symptoms such as chronic pelvic pain, painful menstrual bleeding (dysmenorrhea), and abdominal cramps.

 

Q: Will Jitodieno 2 Tablet stop my monthly periods?

A: Yes, it frequently changes your bleeding patterns. Many women experience irregular spotting, very light periods, or the complete cessation of periods (amenorrhea) while taking this medication. This is a common and expected pharmacological effect, but you should consult your doctor immediately if you experience excessively heavy or prolonged bleeding.

 

Q: Can I use Jitodieno 2 Tablet as a routine contraceptive pill?

A: No, Jitodieno 2 Tablet is not a contraceptive on its own. While it does suppress ovulation in many users, it is not approved or reliable as a standalone birth control pill. However, it can be prescribed in combination with other specific medications for contraception. To effectively prevent pregnancy while taking this medication as a standalone therapy for endometriosis, you must use a reliable, non-hormonal barrier method, such as condoms.

 

Q: How long do I need to take Jitodieno 2?

A: The duration of treatment is highly subjective and depends entirely on the severity of your endometriosis and how well you respond to the therapy. Your healthcare provider will determine the appropriate timeline based on clinical monitoring; you should follow their instructions strictly and never discontinue the medication abruptly without consulting them.

 

Q: Does Jitodieno 2 Tablet affects fertility?

A: Jitodieno 2 Tablet contains Dienogest, which acts as an ovulation inhibitor. Consequently, your natural menstrual cycle and fertility are temporarily suppressed while you are actively taking the medication. However, this effect is fully reversible; normal ovarian function and fertility typically return within one to two months after discontinuing the treatment. Because it suppresses ovulation, this medication is not recommended for women who are actively trying to conceive.

 

 

 

References:

1. DIENOGEST. Accessed on: 21st July 2026. Click Here

2. VISANNE® 2 mg dienogest tablets. PATIENT INFORMATION LEAFLET. Last Revised: 01 March 2022. Accessed on: 21st July 2026. Click Here

3. JAMP Dienogest. Dienogest Tablets 2 mg. Progestin. PRODUCT MONOGRAPH. Last Revised: April 20, 2020. Accessed on: 21st July 2026. Click Here