Jitoace SEPA Tablet (10 Tab)

Medicine Information

Jitoace SEPA Tablet Overview:

Jitoace SEPA Tablet is a combination medicine used to relieve acute to chronic pain, swelling, and inflammation associated with various medical conditions.

It contains Aceclofenac (an anti-inflammatory agent), which helps reduce pain and inflammation, Paracetamol (analgesic and antipyretic), which provides pain relief and lowers fever, and Serratiopeptidase (a proteolytic enzyme), which reduces swelling and supports faster healing. Together they provide relief from migraine, headache, toothache, menstrual pain, body aches, fever-related discomfort, joint pain, muscle pain, back pain, and pain after injury or surgery. It is also useful in musculoskeletal disorders and post-operative inflammation.

By easing discomfort and inflammation, Jitoace SEPA Tablet helps patients recover faster and improves daily comfort and mobility.

Composition:

Each film coated tablet contains- Aceclofenac: 100 mg, Paracetamol: 325 mg, Serratiopeptidase (As enteric coated granules eq. to enzyme activity 30,000 units) : 15 mg.

Colours: Sunset Yellow & Titanium Dioxide.

Uses & Benefits of Jitoace SEPA Tablet:

• Effective Pain Management- Helps reduce muscular aches, strains, and injury-related pain.
• Joint Pain Management- Relieves pain and stiffness in osteoarthritis, rheumatoid arthritis, and other joint conditions.
• Tooth Pain Control- Provides effective relief after dental procedures, extractions, or infections.
• Back Pain Relief- Eases discomfort from lower back pain, cervical spondylosis, and spinal strain.
• Anti-inflammatory Action- Helps decrease inflammation and swelling at the site of pain.
• Post-Surgical Use- Manage pain and swelling after surgery.
• Faster Healing- Supports tissue repair and improves recovery.

How Does Jitoace SEPA Tablet Work:

Jitoace SEPA Tablet works through a combined mechanism of action with its three active ingredients.

Aceclofenac helps control pain and inflammation by stopping the release of chemicals that cause swelling at the affected area. Paracetamol works in the brain to relieve pain and bring down fever. Serratiopeptidase is an enzyme that reduces swelling by breaking down unwanted proteins and improving blood flow to the injured area. It also helps remove damaged tissue and excess fluid, which supports faster healing. Together, these ingredients provide strong pain relief, reduce inflammation, and help the body recover more comfortably and quickly.

Dosage of Jitoace SEPA Tablet:

• Usage Direction

Take Jitoace SEPA Tablet strictly according to your doctor’s instructions, following the prescribed dose and timing. Jitoace SEPA Tablet should be swallowed whole with a glass of water without crushing, chewing, or breaking it, preferably at the same time each day. Do not stop or alter the dose of Jitoace SEPA Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of Jitoace SEPA, consult with your doctor or pharmacist.

• Missed Dose

If you miss a dose of Jitoace SEPA Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one. Setting daily reminders using phone alarms or medication management apps can help establish consistent dosing habits. If you frequently miss doses, discuss with your healthcare provider whether a different dosing schedule might be more suitable for your lifestyle and treatment needs.

•  Overdose

If an overdose of Jitoace SEPA Tablet is suspected, seek emergency medical attention immediately. Possible symptoms may consist of intense nausea, vomiting, stomach pain, dizziness, or even more severe complications such as liver damage or bleeding. The risk of overdose occurs when you take more than the prescribed dose; in that case, professional intervention is required.

Contraindications of Jitoace SEPA Tablet:

Do not take Jitoace SEPA Tablet if you are hypersensitive or allergic to Aceclofenac, Paracetamol, Serratiopeptidase, or any of the components of this medicine. If you previously had any allergic reactions to ibuprofen, aspirin, or other NSAIDs (e.g., asthma, rhinitis, angioedema, or urticaria). Avoid this medicine if you have a current or past history of stomach ulcers, repeated gastric bleeding, or bleeding disorders. It should not be used in people with severe heart disease, uncontrolled high blood pressure, serious liver damage, or kidney problems.

Precautions & Warnings of Jitoace SEPA Tablet:

Jitoace SEPA Tablet should be used carefully, especially if taken for a long time. Your doctor may adjust the dose and regularly check liver and kidney function. Inform your doctor if you have high blood pressure, heart disease, asthma, diabetes, or any liver or kidney problems. Elderly patients need extra caution, as they have a higher risk of stomach ulcers, bleeding, and drug side effects. People with a history of stomach disorders should use it carefully. Patients with heart conditions or previous stroke require close monitoring. If you are planning surgery, inform your doctor, as the medicine may need to be stopped. Long-term use should only be under medical supervision with regular health check-ups.

Label Warning: "Taking more than the daily dose of Paracetamol may cause serious liver damage or allergic reactions (e.g. swelling of the face, mouth and throat, difficulty in breathing, itching or rash)".

Side Effects of Jitoace SEPA Tablet:

Jitoace SEPA Tablet may cause some side effects, which are usually mild and improve as your body adjusts. Common side effects include nausea, vomiting, stomach pain, indigestion, heartburn, diarrhea, constipation, dizziness, headache, fatigue, and loss of appetite. Some people may notice a skin rash or itching.

Serious side effects are rare but need immediate medical help. These include black or bloody stools, vomiting blood, severe stomach pain, swelling of the face or throat, breathing difficulty, chest pain, yellowing of the eyes or skin, dark urine, unusual swelling of legs, or reduced urine output. If you notice any unusual or worsening symptoms while taking Jitoace SEPA Tablet, contact your doctor promptly for proper evaluation and treatment.

Safety Related Concerns of Jitoace SEPA Tablet:

• Pregnancy

Jitoace SEPA Tablet is should be used carefully during pregnancy, and only if necessary after discussing risks with your doctor. It may harm the developing baby, particularly in the later stages, so stop it right away if you become pregnant and seek alternatives.

• Breastfeeding

Breastfeeding mothers are advised to avoid Jitoace SEPA Tablet as it may pass through breast milk and can cause side effects in breastfed babies. Therefore, it is important to consult your doctor before taking Jitoace SEPA Tablet while breastfeeding.

• Alcohol

Avoid drinking alcohol while taking Jitoace SEPA Tablet, as it significantly increases the risk of liver damage and stomach bleeding. Please consult with your doctor.

• Using Machinery & Driving

Jitoace SEPA Tablet may cause side effects like dizziness, vertigo, drowsiness, fatigue, or visual disturbances in some people. Patients should use caution and avoid driving or operating machinery until they are sure the medication does not affect their alertness.

• Food Interactions

The interaction of certain foods with the Jitoace SEPA Tablet is not known. Hence, it is preferred to be taken with meals or after eating to lower the risk of stomach irritation. It is also vital to follow a healthy diet by avoiding spicy, deep-fried, and acidic foods to prevent additional gastrointestinal irritation and facilitate better absorption.

• Drug Interactions

Jitoace SEPA Tablet may interact with other drugs, potentially compromising their effectiveness. It could lower the efficacy of antihypertensive medications or diuretics, which might cause kidney issues. If you are taking a potassium-sparing diuretic, then potassium levels should be closely monitored. Furthermore, it can elevate lithium or digoxin levels by decreasing their elimination rate. Serratiopeptidase has the potential to interact with anticoagulant or antiplatelet drugs, including heparin, warfarin, and ibuprofen, which might reduce their effectiveness by delaying the clotting of blood, leading to a possibility of bleeding or bruising. Paracetamol interacts with medications metabolized by liver enzymes. Always inform your healthcare provider and pharmacist about all kinds of drugs you are taking to avoid complications.

Storage of Jitoace SEPA Tablet:

Store protected from light and moisture, at a temperature not exceeding 25°C. Keep Jitoace SEPA Tablet out of reach of children. Not for veterinary use.

Do not use beyond the expiration date, and dispose of unused tablets properly through pharmaceutical take-back programs.

Additional Notes:

• Combine Jitoace SEPA with gentle physiotherapy, light stretching, and adequate rest to improve mobility and pain relief.
• Stay well hydrated to help serratiopeptidase reduce swelling effectively.
• For injuries, follow the R.I.C.E. method (Rest, Ice, Compression, Elevation) to support anti-inflammatory action.
• Avoid sudden strenuous activity or heavy lifting, especially if you experience back or muscle pain, to prevent delayed recovery.
• After surgery, follow medical advice on wound care, rest, and follow-ups; the medicine supports but does not replace post-operative care.
• If pain persists, worsens, or keeps recurring, consult a doctor instead of repeated use.
• Maintain a balanced, protein- and vitamin-rich diet to aid tissue repair and recovery.
• Keep the medicine out of children’s reach and do not share it with others.

Frequently Asked Questions (FAQs):

Q1. What is Jitoace SEPA Tablet used for?

A: Jitoace SEPA Tablet is used for pain relief, such as back pain, joint pain, muscle pain, tooth pain, migraine, inflammation, and swelling in conditions like arthritis, muscle or sports injuries, and post-surgery recovery.

Q2. How does Jitoace SEPA Tablet work in pain and inflammation?

A: The three components of Jitoace SEPA Tablet work synergistically for managing pain and inflammation. Aceclofenac and Paracetamol block the chemical messenger prostaglandin, which causes pain and inflammation at the injured site. On the other hand, Serratiopeptidase reduces swelling and pain by loosening the blood vessels around the affected part and improving blood circulation. Concomitantly, they work and help reduce pain and inflammation.

Q3. Does Jitoace SEPA Tablet cause stomach problems?

A: Aceclofenac is one of the active ingredients in the Jitoace SEPA Tablet, and like most NSAIDs, it can cause acidity or stomach upset. Your doctor may suggest you take it after food to help minimize this.

Q4. Is Jitoace SEPA Tablet safe for long-term use?

A: Generally, Jitoace SEPA Tablet is used for short-term use. Taking it for a long time or in high doses may increase the risk of stomach problems such as acidity, ulcers, or bleeding, as well as liver and kidney damage and heart-related risks. The duration of treatment is decided by the doctor based on your condition and symptoms. Therefore, long-term use should be done only under strict medical supervision.

Q5. Is Jitoace SEPA Tablet safe for elderly patients?

A: Jitoace SEPA Tablet can be used in elderly patients, but with extra caution and only under a doctor’s supervision. Older adults are more sensitive to side effects, especially stomach irritation or bleeding, kidney function changes, and heart-related risks. Doctors usually prescribe the lowest effective dose for the shortest possible duration. Elderly patients should stay well hydrated and report symptoms like stomach pain, black stools, reduced urine output, dizziness, or swelling immediately. Regular monitoring may be advised if treatment continues for more than a few days.

Q6. Can Jitoace SEPA Tablet be used for post-surgery pain and swelling?

A: Yes, Jitoace SEPA Tablet can be used for post-surgery pain and swelling, due to the inclusion of serratiopeptidase, a proteolytic enzyme. It acts as a vasodilator, making it particularly effective for reducing post-surgical edema and pain.

Remarks:

1. ACYCLOSURE SP. Aceclofenac, Paracetamol & Serratiopeptidase Tablets. Last Revised: December 2021. Accessed on: 2nd January 2025. Click Here

1. Ankinac-SP. Aceclofenac, Paracetamol, Serratiopeptidase & Tablets. For consumer information only. Accessed on: 2nd January 2025. Click Here