Medicine Information
About Dablexa 150 mg Capsule:
Each hard cellulose Dablexa 150 mg capsule contains Dabigatran Etexilate Mesilate equivalent to Dabigatran Etexilate 150 mg and Excipients q.s.
Dabigatran etexilate belongs to a group of medicines called anticoagulants. It works by blocking a substance in the body which is involved in blood clot formation.
After administration, dabigatran etexilate (pro-drug) is rapidly converted to dabigatran (active drug) by esterase-catalyzed hydrolysis. Dabigatran is a potent, competitive, reversible direct thrombin inhibitor. It prevents the thrombin-mediated conversion of fibrinogen into fibrin during the coagulation cascade, which inhibits the development of thrombus.
Dabigatran also inhibits free thrombin, fibrin-bound thrombin, and thrombin-induced platelet aggregation.
Use of Dablexa 150 mg Capsule:
Dablexa 150 mg capsule is prescribed to:
- Reduce the risk of stroke & systemic embolism in patients with non-valvular atrial fibrillation (NVAF).
- Prevent postoperative venous thromboembolism (the formation of blood clots in the veins after knee or hip replacement surgery).
- Treat Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE).
- Reduce the risk of recurrence of Deep Venous Thrombosis (DVT) and Pulmonary Embolism (PE) in patients who have been previously treated.
Usage direction of Dablexa 150 mg Capsule:
- Dablexa 150 mg capsule should be taken orally.
- Dablexa 150 mg capsule is taken whole with the help of water.
- Do not crush, chew or break the capsule.
- Do not stop or skip the medicine without the physician’s advice.
- Do not consume more than the prescribed quantity.
Precaution & Related Information of Dablexa 150 mg Capsule:
- If allergic to this medicine inform the physician immediately.
- If find any complication inform the physician immediately.
- Precaution should be taken if you have a history of severely reduced kidney and liver functions.
- Individual with active bleeding or an increased tendency of bleeding should discuss with the healthcare professional prior to the treatment.
- Consult with the physician during pregnancy & lactation.
- Store in a dry place, at a temperature not exceeding 30°C.
- Keep out of reach of children.
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