Biggaba NT Tablet (10 Tab)

Medicine Information

Biggaba NT Tablet Overview:

Biggaba NT Tablet is a combination medicine containing Pregabalin and Nortriptyline, used for the effective management of neuropathic (nerve-related) pain.

It is commonly prescribed for conditions such as diabetic neuropathy, post-herpetic neuralgia, fibromyalgia, neuropathic low back pain, spinal cord injury-associated pain, and other chronic nerve pain disorders.

Neuropathic pain is different from regular pain because it occurs due to damage or malfunction of the nervous system, rather than injury to muscles or tissues. This type of pain often feels like burning, tingling, stabbing, or electric-shock sensations and may not respond well to single-drug treatment.

Biggaba NT Tablet works through a dual mechanism of action, providing a synergistic effect for better pain control. Pregabalin helps calm overactive nerves by reducing abnormal pain signals, while Nortriptyline enhances natural pain-relieving chemicals in the brain and spinal cord. Together, they target pain pathways at multiple levels, offering comprehensive and long-lasting relief from chronic nerve pain.

Composition:

Each film coated bilayered Biggaba NT Tablet contains- Nortriptyline Hydrochloride eq. to Nortriptyline: 10.0 mg, and Pregabalin (as sustained-release form): 75.0 mg.

Colours: Ferric Oxide Yellow & Titanium Dioxide

Uses & Benefits of Biggaba NT Tablet:

Biggaba NT Tablet is primarily used to treat neuropathic pain, including:

• Diabetic Neuropathy: Helps manage nerve pain caused by long-term high blood sugar levels. This condition often leads to pain, numbness, burning, or tingling sensations, especially in the hands and feet.
• Post-herpetic Neuralgia: Provides relief from ongoing nerve pain or sharp, stabbing sensations that may persist even after a shingles (herpes zoster) infection has healed.
• Spinal Cord Injury–Related Pain: Helps reduce chronic pain affecting the spinal cord or central nervous system due to nerve injury or trauma.
• Fibromyalgia: Helps reduce musculoskeletal pain associated with tiredness, sleep problems, difficulty concentrating, and mood changes such as anxiety or depression.

How Does Biggaba NT Tablet Work:

Biggaba NT Tablet contains Pregabalin and Nortriptyline, which work together through two different mechanisms to manage neuropathic pain effectively.

Pregabalin acts on specific sites, particularly the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, to reduce the release of nerve chemicals responsible for sending pain signals. Calming overactive or damaged nerves, it helps lower abnormal nerve activity that leads to neuropathic pain.

Nortriptyline works in the brain and spinal cord by increasing the levels of natural pain-controlling chemicals (serotonin and norepinephrine). These chemicals help reduce the transmission of pain signals and strengthen the body’s own pain-relief pathways. It also supports emotional well-being, which is important because long-term pain is often linked with anxiety and low mood.

Together, these combined actions provide comprehensive pain management by addressing both nerve damage and pain processing in the nervous system, offering effective and long-lasting relief from chronic nerve pain.

Dosage of Biggaba NT Tablet:

• Usage Direction:

Biggaba NT Tablet should be taken strictly as per the doctor’s advice, following the prescribed dose and timing. Biggaba NT Tablet should be swallowed whole and not to be crushed, chewed or breaked. Take Biggaba NT Tablet preferably at the same time each day. Do not stop or alter the dose of Biggaba NT Tablet without consulting your doctor, as this may prevent you from achieving the desired outcome. If you are unsure about the administration procedures of this medication, consult with your doctor or pharmacist.

• Missed Dose:

If you miss a dose of Biggaba NT Tablet, take it as soon as you remember on the same day. But, if it is almost time for your next scheduled dose, skip the one you missed and continue following your regular dosing schedule. Do not attempt to take two doses if you have forgotten one.

You can set reminders on your smartphone, keep drug organizer boxes, or use other audio-visual technologies to prevent missing a dose.

• Overdose:

If you accidentally take Biggaba NT Tablet more than your prescribed dose, seek immediate medical advice, as this may lead to serious side effects. Symptoms may include extreme sleepiness, confusion, or rapid heartbeat.

Contraindications of Biggaba NT Tablet:

Biggaba NT Tablet is not recommended in children below six years old.

Do not take Biggaba NT Tablet if you are allergic to Pregabalin, Nortriptyline, or any of its ingredients. This medicine should also be avoided in people with severe liver problems, bipolar disorder (mania), heart attack, heart block or other irregular heart rhythms, and urinary retention.

Biggaba NT Tablet is not recommended for children under six years of age.

Precautions & Warnings of Biggaba NT Tablet:

Biggaba NT Tablet should be used with care and under medical supervision. Patients should be monitored for signs of suicidal thoughts, especially when starting treatment or changing doses, and caution is advised for those with a history of depression, anxiety, or previous suicide attempts. The medicine may cause dizziness, drowsiness, or poor coordination, increasing the risk of falls, particularly in older adults. Heart patients should be monitored due to potential effects on heart rhythm and blood pressure, while people with diabetes should watch their blood sugar closely. Kidney function should be checked before starting treatment, and dose adjustments may be needed in impaired kidney function. The tablet should not be stopped suddenly to avoid withdrawal symptoms. Patients should inform their doctor about all medications and health conditions, including substance abuse history or family history of mood disorders, and report any new or unusual symptoms promptly.

Side Effects of Biggaba NT Tablet:

Biggaba NT Tablet may cause some side effects, which are usually mild and improve as your body adjusts. Common side effects include dizziness, drowsiness, dry mouth, blurred vision, constipation, weight gain, swelling of hands and feet, difficulty concentrating, and fatigue. Elderly patients may experience urinary retention, increased heart rate, excessive sweating, or confusion. Some may have nausea, stomach upset, or appetite changes, while coordination problems, memory issues, or mood changes can also occur.

Serious side effects are rare but require immediate attention, including allergic reactions (rash, swelling, difficulty breathing), irregular heartbeat, chest pain, significant blood pressure changes, angioedema, vision changes, unexplained muscle pain, seizures, or new mental health symptoms such as increased anxiety, depression, or suicidal thoughts. However, if these symptoms continue, it is crucial to consult your doctor.

Safety Related Concerns of Biggaba NT Tablet:

• Pregnancy:

Biggaba NT Tablet should be used during pregnancy only if the benefits outweigh potential risks. Both pregabalin and nortriptyline can affect fetal development. Pregnant women or those planning pregnancy should discuss alternatives with their doctor. If pregnancy occurs while taking this medicine, contact your healthcare provider immediately to evaluate whether to continue or adjust treatment.

• Breastfeeding:

It is recommended to avoid using the Biggaba NT Tablet while breastfeeding, as Pregabalin may pass through breast milk and could potentially affect the breastfed child. On the other hand, Nortriptyline is strictly contraindicated for nursing mothers and children six years old and below.

• Alcohol:

Avoid alcohol consumption while taking Biggaba NT Tablet, as it significantly increases the sedative effects (dizziness/drowsiness). Additionally, excessive consumption of alcohol may lead to overdose and potentially increase the risk of suicidal attempts.

• Food Interactions:

Biggaba NT Tablet can be taken with or without food, although specific dietary choices may affect its effectiveness. It is advisable to avoid grapefruit or grapefruit juice, as they may interact with the medication and cause undesirable side effects. To effectively utilize Biggaba NT, maintain a healthy, balanced diet, and avoid high-calorie, sugary foods. Ensure you drink enough water to stay hydrated and include vegetables and fruits in your diet, which are beneficial for nerve health.

• Drug Interactions:

Biggaba NT Tablet can interact with numerous medications, and it is important to inform your healthcare if you are taking.

Biggaba NT Tablet may interact with several medicines and should be used with caution when taken together with ethanol (alcohol), lorazepam, and other sedatives, as this may increase drowsiness and breathing problems. Monoamine oxidase inhibitors (MAOIs) should not be used with this medicine due to the risk of severe reactions. Interactions may also occur with medicines affecting blood pressure or heart function, including ephedrine, isoprenaline, noradrenaline, phenylephrine, Phenylpropanolamine, guanethidine, debrisoquine, bethanidine, and clonidine. Other interacting medicines include barbiturates, cimetidine, fluoxetine, phenothiazines, carbamazepine, propafenone, flecainide, encainide, quinidine, anticholinergic drugs, and valproic acid.

Always inform your healthcare provider and pharmacist about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, minerals, and herbal supplements, to avoid potential interactions.

• Using Machinery & Driving:

Biggaba NT could frequently causes significant dizziness and blurred vision. Do not drive or operate heavy machinery until you are certain you can perform these activities safely.

Storage Information of Biggaba NT Tablet:

Store in a dry place at a temperature not exceeding 30°C. Protect from light.

Check expiration dates regularly and Dispose of expired or unneeded medications properly through local regulations or pharmacy take-back programs rather than flushing or household trash disposal.

Keep Biggaba NT Tablet out of reach of children.

Additional Information:

• For diabetic neuropathy, maintaining stable blood sugar levels is critical for the medicine's effectiveness.
• Gentle exercise or physiotherapy can help maintain muscle strength and improve mobility while managing nerve pain.
• Eat a healthy, balanced diet and maintain an ideal body weight if you see weight gain as per the instructions of your doctor or nutritionist.
• Take the medicine at the same time as prescribed to maintain consistent levels in the bloodstream.
• Avoid direct sunlight or tanning beds while taking Biggaba NT, as it may increase sun sensitivity. Use sunscreen and protective clothing when going outdoors during the day.

Frequently Asked Questions (FAQs)

Q. Why is Biggaba NT Tablet used?

A: Biggaba NT Tablet is used to treat neuropathic pain, which is pain caused by nerve damage. It is commonly prescribed for conditions such as diabetic neuropathy, post-herpetic neuralgia, spinal cord injury–related pain, and fibromyalgia. The medicine helps reduce nerve-related pain sensations like burning, tingling, or stabbing pain, especially when simple painkillers are not effective.

Q. Is Biggaba NT a habit-forming medicine?

A: Biggaba NT Tablet is not usually considered a habit-forming medicine. However, it contains pregabalin, which may cause dependence in some people if used for a long time or in higher doses, especially in those with a history of substance abuse. Nortriptyline does not cause addiction, but stopping it suddenly may lead to discomfort. Always take Biggaba NT Tablet exactly as prescribed and do not stop or change the dose without consulting your doctor.

Q. How long will I need to take Biggaba NT Tablet?

A: The duration of treatment is decided by the doctor based on your medical condition, severity and how well you tolerate this medicine. Some patients may need it for a few weeks, while others with long-term nerve pain may require longer use. Your doctor will decide the correct duration and may adjust the dose over time. Do not stop taking the medicine suddenly without medical advice, even if you feel better.

Q. Can I stop taking Biggaba NT when my pain is gone?

A: You should not stop taking Biggaba NT Tablet on your own, even if your pain has improved. Stopping it suddenly may cause withdrawal symptoms or a return of pain. Always consult your doctor before stopping the medicine, as the dose usually needs to be reduced gradually to avoid unwanted effects.

Q. Can I take this tablet with my blood pressure medicine?

A: You may be able to take Biggaba NT Tablet with your blood pressure medicine, but it should be done only under a doctor’s guidance. Biggaba NT can sometimes affect blood pressure or increase dizziness, especially when combined with certain blood pressure medicines. Inform your doctor about all medicines you are taking so they can monitor you and adjust doses if needed.

Q. Are there any specific concerns for elderly patients taking Biggaba NT Tablet?

A: Yes, elderly patients need extra caution when taking Biggaba NT Tablet. They may be more sensitive to side effects such as dizziness, drowsiness, confusion, constipation, or difficulty in urination, which can increase the risk of falls. Kidney function may also be reduced with age, so dose adjustments and regular monitoring may be needed. It should always be used under close medical supervision in older adults.

Q. Does Biggaba NT Tablet causes weight gain?

A: Yes, Biggaba NT Tablet may cause weight gain in some people, mainly due to increased appetite or fluid retention. This effect is usually mild but can be more noticeable with long-term use. Maintaining a balanced diet and regular physical activity can help manage weight. If you notice significant or sudden weight gain, inform your doctor.

Reference:

1. Abridged Prescribing Information: Active Ingredient: PREGABID NT 50/75 tablets contain pregabalin 50mg / 75 mg +Nortriptyline 10mg. Last Revised: 24th February 2020. Accessed on: 21st January 2026. Click Here

2. Nuring NT Tablets. centaurpharma. Accessed on: 21st January 2026. Click Here

3. Generic Name Pregabalin 75mg + Nortriptyline 10mg Tablets. Trade Name Neurokem- NT. Accessed on: 21st January 2026. Click Here